Table 1.

Total Testis, Uterus, and Ovary Weight and Number of Embryos Flushed from the Oviducts of Mice on Different Genetic Backgrounds

Genetic background Av. weight ±s.d.+/+ −/− Percent reduction t-test P-value
A. Testis
R1208.2 ± 29.4 (n = 15)154.0 ± 37.6 (n = 16)26<0.001
W9.5191.9 ± 14.3 (n = 6)156.1 ± 17.1 (n = 7)190.002
C57186.8 ± 15.3 (n = 13)159.9 ± 17.9 (n = 12)14<0.001
B. Uterus
R1114.9 ± 23.0 (n = 6)79.7 ± 27.8 (n = 7)310.032
W9.5122.8 ± 31.7 (n = 9)82.5 ± 19.0 (n = 5)330.024
C5794.5 ± 14.3 (n = 10)52.9 ± 20.1 (n = 7)44<0.001
C. Ovary
R110.4 ± 3.8 (n = 6)11.2 ± 1.8 (n = 7)N.R.0.635
W9.58.7 ± 2.1 (n = 9)8.8 ± 2.4 (n = 5)N.R.0.878
C577.3 ± 2.2 (n = 10)8.0 ± 1.8 (n = 7)N.R.0.513
D. No. of embryos
R17.8 ± 5.0 (n = 6)4.7 ± 3.3 (n = 7)N.R.0.198
W9.55.9 ± 3.5 (n = 9)3.4 ± 3.1 (n = 5)N.R.0.210
C574.9 ± 2.9 (n = 10)4.6 ± 3.6 (n = 7)N.R.0.838

[i] Ten-week-old +/+ and −/− mice were used. Uteri, ovaries, and embryos were collected at day 0.5 of vaginal plug using previously unmated females. Weight is in mg. (N.R.) Not relevant, asP-value is insignificant.