Breakpoint sequence motif frequencies in three classes of sequence in six Muller elements in D. pseudoobscura
| Muller element | Breakpoints | Noncoding | Coding | |||||
|---|---|---|---|---|---|---|---|---|
| na | (% ± SD)b | n | (% ± SD) | χ2 | n | (% ± SD) | χ2 | |
| A | 210 | 33.8 ± 3.3 | 1698 | 15.3 ± 0.9 | 45.5c | 1851 | 0.8 ± 0.2 | 513.6c |
| B | 135 | 43.0 ± 4.3 | 2031 | 12.9 ± 0.7 | 90.3c | 2124 | 0.8 ± 0.2 | 703.0c |
| C | 205 | 39.0 ± 3.4 | 2082 | 11.4 ± 0.7 | 119.4c | 2276 | 0.7 ± 0.2 | 733.4c |
| D | 141 | 42.6 ± 4.2 | 2068 | 14.3 ± 0.8 | 78.3c | 2159 | 0.6 ± 0.2 | 758.0c |
| E | 223 | 38.1 ± 3.3 | 2636 | 10.3 ± 0.6 | 146.1c | 2923 | 0.4 ± 0.1 | 985.8c |
| F | 7 | 57.1 ± 18.7 | 76 | 44.7 ± 5.7 | 0.4 | 63 | 17.5 ± 4.8 | 5.9c |
[i] aThe total number of sequences within each category.
[ii] bThe percentage of sequences within each category that matched the conserved sequence motif ± standard deviation. The three categories are breakpoints, sequences at the boundary of two conserved linkage groups; noncoding, sequences that are not breakpoints or coding; and coding, sequences of protein-coding genes including introns.
[iii] cProbability of the χ2 value for the heterogeneity test with one degree of freedom is ≤0.05 after applying a Bonferroni correction for multiple comparisons (Rice 1989). A χ2 heterogeneity test is used to determine if the frequency of the breakpoint motif is significantly different between either the noncoding or coding regions.