Analysis of RBP expression dynamics in cardiac cells. (A) Volcano plots showing differential RBP gene expression across sequential time point comparisons during iPSC-to-iCM differentiation. (D0, D2, D4, D30) Days of differentiation. (B) Dot plot representing single-cell RBP gene expression for candidates upregulated in D30 iCMs across contractile and noncontractile cells in ex vivo fetal heart tissue and D30 in vitro iCMs. (C) Histogram of DeepBIND-predicted RBP binding sites frequencies in transcripts displaying DTA. (D) Histogram of DeepBIND-predicted RBP binding sites frequencies in sequences flanking DTA-associated splice sites.