Tetraploids exhibit longer telomeres than isogenic homozygous diploids. (A) Global TL distributions of the natural North American diploid strain YPS128 and the experimentally generated isogenic tetraploid. (B) Global TL distributions of the natural West African diploid strain DBVPG6044 and the experimentally generated isogenic tetraploid. (C) Boxplots of extremity-specific TL distributions for all extremities, shown for the four strains from A and B (same color code).