Radar plots of performance comparisons on unpaired omics data sets using precision, AUROC, and AUPRC. (A) For GRN reconstruction, the radar plot shows the performance comparisons of PRISM-GRN using unpaired data on the A549 and GM12878 data sets, compared with results from paired data, as well as with Grace and GeneLink. On the hESC and mESC data sets that with no paired data, PRISM-GRN is compared with Grace and GeneLink. (B) For causality prediction, the radar plot illustrates the performance comparison of PRISM-GRN, Grace, and GeneLink on the same data sets. PRISM-GRN can achieve comparable results to those obtained with paired data and those obtained by Grace and GeneLink.