Overview of the Ralphi framework for haplotype assembly. As an example, a fragment graph is constructed from a set of six DNA fragments covering seven SNPs (the allele containing a sequencing error is shown in red), with negative agreement edges shown in blue, and conflict edges, in red (the thickness of the edge corresponds to edge weight). Fragments are partitioned into final haplotypes through an iterative process wherein the agent assigns a node to a haplotype in each step based on the prediction given by the actor-critic network operating over the fragment graph embedding. The final haplotypes are assembled by computing the consensus of the fragments in each partition.