Table 1.

Studies investigating the origin of ORFans in bacteria

Year of publicationHypotheses investigatedTaxa investigatedReference
2024Emergence from noncoding sequences, frameshifting, phage originVarious taxa in human gut microbiomeVakirlis and Kupczok 2024
2023Emergence from noncoding sequencesBacillus genusKarlowski et al. 2023
2021FrameshiftingEscherichia coliWatson et al. 2021
2015Phage originVariousLobb et al. 2015
2010Emergence from intergenic sequences, frameshifting, phage originVariousYomtovian et al. 2010
2009Phage originVariousCortez et al. 2009
2006Phage originVariousYin and Fischer 2006
2004Phage originEscherichia coliDaubin and Ochman 2004a