SNV- and indel-calling performance across sequencing platforms. F-score, precision, and recall distribution for SNVs (left) and indels (right) across the different sequencing platforms. For Illumina, MGI, and ONT (both R9 and R10), displayed are performance metrics in high-confidence regions genome-wide. In addition, for ONT R9 and R10, shown are also performance metrics in exonic regions. Each boxplot encapsulates the corresponding metrics for the three Coriell samples with truth sets available (GM24143, GM24149, and GM24385).