Comparing architectural stripes Quagga finds from Hi-C or Micro-C, their behavior is assessed as CTCF-stripes, EP-stripes, or as indeterminate stripes. (A) The distribution of stripe-lengths on Hi-C data falls into a majority around CTCF-stripe expected lengths. (B) Micro-C is similarly distributed, with less indeterminate stripes compared with indeterminate. (C) In an example stripe in H1-hESC Micro-C, no CTCF signal is present but H3K4me2 is present, suggesting this is an EP-stripe. (D) We show that global stripe detection on region capture Micro-C data recapitulates our observations in Hi-C and Micro-C for gastrointestinal stromal tumor (GIST-T1) cells.