Chromatin occupancy profiling simultaneously reveals nucleosome and TF changes. (A) Example of changing nucleosome occupancy at the PHO89 locus when PHO85 is deleted. (B) Example of changing TF occupancy in the promoter region of MET10 when CBF1 is deleted. (C) Chromatin changes at the GAL1-10 locus as a result of deleting the repressor GAL80. For both GAL10 and GAL1, nucleosomes exhibit decreased occupancy in the gene body, whereas TFs exhibit increased occupancy in the promoter. (D) Bar plots displaying the log₂ fold change (log₂(FC)) in nucleosome and TF occupancy at both the GAL10 and GAL1 genes as a result of deleting GAL80.