Clade and plasmid distribution in K. pneumoniae ST258 and E. hormaechei ST171 isolates. For (A) ST258 and (B) ST171 phylogenetic trees, the annotations denote the bla_KPC allele (inner ring) and associated Tn4401 subtype (second ring) as well as the genetic location of bla_KPC (chromosome and plasmid cluster; outer rings) for each isolate. Clade designations refer to groups of isolates within each ST with pairwise genetic distances of ≤25 SNPs.