Table 1.

Computational resources needed for a database built on 10,470 reference genomes and 756 queries (50 M short reads)

Running timePeak memory
QueryLibraryQueryLibrary
Kraken 288 sec, 96 threads3.5 h, 128 threads47 GB50 GB
CLARK676 sec, 96 threads13.5 h, 128 threads150 GB370 GB
CONSULT-II2191 sec, 96 threads19 h, 128 threads141 GB157 GB
KRANK-hs1167 sec, 96 threads4.5 h, 32 × 4 threads51 GB32 GB per batch
KRANK-lw787 sec, 96 threads2.5 h, 32 × 4 threads13 GB8 GB per batch

[i] Measurements for both queries and library building were performed on a machine with 2.2 GHz AMD EPYC 7742 processors. Reported library building times are for 256 and 512 batches, respectively, for KRANK-lw and KRANK-hs, each with four threads, distributed across 32 cluster nodes and run in parallel.