Markup | Genome Research

Table 2.

Estimated spatial partial correlations versus the association strength determined by SpaCeNet for the four top-ranked associations discussed in the main text

	$j k^{'}$	$j^{'} k$	$\frac{1}{2} (j^{'} k + j k^{'})$	Δρ⁽¹⁾
Flt1–Mbp	−0.560	−0.557	−0.558	0.327
Ctgf–Gja1	−0.118	−0.119	−0.119	0.102
Ctgf–Pcp4	−0.227	−0.234	−0.231	0.083
Reln–Sst	−0.174	−0.205	−0.190	0.078

[i] Here, $j k^{'}$ corresponds to spatial partial correlations between variable j and $k^{'}$ conditioning on $j^{'}$ and k. An analogous definition holds for $j^{'} k$ and the respective average is given by $\frac{1}{2} (j^{'} k + j k^{'})$ . SpaCeNet's leading order association strength is given by Δρ⁽¹⁾ with positive signs corresponding to negative associations in line with the definition of the precision matrix of ordinary GGMs.