The performance of DeltaSplice and baseline methods in predicting splicing-altering mutations at sQTLs. GTEx brain sQTLs were used as foreground, and common SNPs were used as background. Only variants ≤200 bp from cassette exons were used for analysis. Foreground and background variants were combined and ranked by |ΔPSI| predicted by each method, and the enrichment of sQTLs among top k predictions with varying k is shown. The inset shows the enrichment of sQTLs among top 20,000 variants.