Table 2.

The 10 most significantly enriched GO biological process terms of genes that experienced hard sweeps only in the Orkney vole population

Term IDTerm namePadjTerm sizeIntersection size
GO:0006955Immune response5.07 × 10−11179417
GO:0048002Antigen processing and presentation of peptide antigen5.17 × 10−8716
GO:0002478Antigen processing and presentation of exogenous peptide antigen7.13 × 10−8305
GO:0042832Defense response to protozoan1.18 × 10−7335
GO:0001562Response to protozoan1.88 × 10−7365
GO:0019884Antigen processing and presentation of exogenous antigen2.17 × 10−7375
GO:0019882Antigen processing and presentation9.88 × 10−71156
GO:0019886Antigen processing and presentation of exogenous peptide antigen via MHC class II2.03 × 10−6184
GO:0002495Antigen processing and presentation of peptide antigen via MHC class II4.85 × 10−6224
GO:0002504Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II7.03 × 10−6244

[i] Padj refers to P-value of enrichment adjusted with the g:SCS method for multiple testing correction. Term size refers to the number of genes in the GO term. Intersection size refers to the number of genes under hard sweep. All the GO terms listed are immune related.