Table 1.

Features of chromatin environments of MPRA library sequences

GroupHistone marksTypical distance to TSSCRX-dependent accessibilityTiming and specificity of accessibilityNo. of CREs in MPRA library
H3K4me3H3K27ac
A++0–5 kbIndependentOpen in other cell types, always accessible249
DependentRetina-specific, late accessibility632
C−+5–500 kbIndependentRetina-specific, early accessibility311
DependentRetina-specific, late accessibility366
D−−5–500 kbIndependentRetina-specific, intermediate accessibility76
DependentRetina-specific, early accessibility89