Enrichment of indel categories with putative RRR categories. Each dot in the matrix represents the enrichment of one type of indel within a specific putative RRR. Indels were first separated into human insertions, human deletions, chimpanzee insertions, or chimpanzee deletions and then further subdivided by size or TE classification. In addition to lineage-specific HERVK(HML2), chimpanzee-specific ERV insertions also include PTERV insertions absent from human genome. Putative CNCC promoter, CNCC enhancer, and iPSC H3K9me3 heterochromatin regions are presented from left to right. Each putative RRR is further classified horizontally into human–chimpanzee invariant, human-biased, and chimpanzee-biased regions. Human-biased and chimpanzee-biased putative CNCC promoters are not shown in the figure because they do not intersect with any indel. The enrichment P-value (BEDTools Fisher's exact test) is displayed as the background grayscale in the matrix, and the enrichment ratio is displayed using both the color and size of each dot. Combinations with no intersections are crossed out.