Structural variation inference across Illumina/10xG, ONT, and PacBio sequencing platforms for sample 51. (A) Ensemble workflow for SV inference, with multiple methods and technologies used to infer SVs, subsequent merging of, first method-specific results, and then technology-specific results, with size and support restrictions applied. (B) SV inference comparison across SVs inferred from platform (x) sequencing experiments, in which “platform” corresponds to sequencing technology, and (x) determines the average alignment read-depth coverage in the tumor sample. Methods-specific breakdown is provided for every sequencing technology. SVs detected in the normal sample are in parentheses. (C) Size distribution for SVs in sample 51T with SVs being either exclusively inferred from either long reads (either ONT, or PacBio, or both), or exclusively from Illumina/10xG short reads, or supported by both long and short reads.