Results of RCK on simulated bulk tumor samples with two clones. (A) False negative rate (FNR) and false positive rate (FPR) of novel adjacencies used by RCK using adjacency utilization parameter P = 0.9 (RCK-0.9) and P = 0.75 (RCK-0.75). (B) Length-weighted segment copy number distances between input copy numbers (${\stackrel{\sim }{\overline{\mathbf{C}}}}^{\mathrm{\prime }}$) and karyotypes inferred by RCK.