Organization of BWS genes and their paralogs in human and Fugu. Gene organization is shown as schematic maps of the human chromosomes and Fugu scaffolds (not to scale; for precise positions on the human chromosomes see Supplemental Table 3). Interruptions of the vertical gray lines representing human chromosomes indicate distances longer than 4 Mb between genes. Human chromosomes (Hs) are labeled by their numbers, as are Fugu sequence scaffolds (Fr). Initially selected genes on human chromosome 11p15.5 (see Fig. 1) are boxed, and their paralogs are shown in black. Additional genes are labeled in gray.