Figure 7.

VISTA: input and output files. Files for submission to VISTA include Sequences (required) and Exons (optional). Repeats are masked in the reference sequence using RepeatMasker upon its submission to VISTA. VISTA generates three output files. The VISTA plot shown here is a subregion of the human ST7 interval compared with the orthologous baboon, cow, mouse, or fugu sequences. Conserved sequences represented as peaks [noncoding (red) and coding (blue)] are shown relative to their positions in the human genome (horizontal axes), and their percent identities (50%–100%) are indicated on the vertical axes. The locations of ST7 exons are indicated by tall blue rectangles, and the direction of transcription is indicated by a horizontal arrow. The locations of repetitive elements are indicated by color rectangles (see Suppl. Fig. 2). The Alignment file shows the alignment between the human reference sequence and the orthologous mouse DNA; coordinates correspond to the positions in the human sequence shown in the VISTA plot. The Conservation file gives the coordinates of the conserved sequences at predefined cutoffs.

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