Regression results for DTH across variant subtypes for rare variants, common variants, and substitutions. The relationship between DTH (log₁₀ bp) and the seven variant subtypes: (A) AT > GC, (B) AT > CG, (C) AT > TA, (D) CpG GC > AT, (E) GC > AT, (F) GC > TA, and (G) GC > CG (plotted as in Fig. 3). Filled points show the conditional variant proportions, scaled by the intercept of the logistic regression. Symbol size represents the proportion of the given variant subtype falling into a given DTH bin. The solid lines are the fitted logistic regression curve, where is the slope fitted in the logistic regression and is the DTH in the th bin. The gray dashed line represents the baseline of no effect.