Figure 5.

Segments of DNA that accumulate many repetitive elements also have less nonrepetitive, noncoding DNA that aligns with mouse. The correlation between NA anc and density of lineage-specific interspersed repeats (RepLS) was measured for human Chromosome 22, using 10-kb overlapping windows with 1-base increments. The overall correlation is r = 0.3353. An empirical P-value was evaluated by performing 100 independent randomizations of the positions of the repeats, while keeping the alignments constant. Local correlations were also computed in the 10-kb sliding windows, for the original data and the 100 randomizations. The blue line represents the histogram of local correlations on the original data, whereas the frequencies of local correlations from the 100 randomizations are summarized by their median curve (dotted line) and envelopes of different shades of brown (50% darkest, 80% lighter, and 100% lightest).

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