Figure 4.

Regression results for recombination rate across variant subtype for rare variants, common variants, and substitutions. The relationship between local recombination rate (log10 cM/Mb) and the observed conditional variant proportion for seven variant subtypes: (A) AT > GC, (B) AT > CG, (C) AT > TA, (D) CpG GC > AT, (E) GC > AT, (F) GC > TA, and (G) GC > CG (plotted as in Fig. 3). Filled points show the conditional variant proportions, scaled by the intercept of the logistic regression. Symbol size represents the proportion of the given variant subtype falling into a given recombination rate bin. The solid lines show the fitted logistic regression curve, where 1974inf12 is the slope fitted in the logistic regression and 1974inf13 is the recombination rate in the 1974inf14 th bin. The gray dashed line represents the baseline of no effect, 1974inf15.

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