Characterization of the ORC1-associated RNAs. ChIP-seq profiles of ORC1, K4me3, and POLR2A at newly identified ORIs, mapping within proximal promoters of known genes (A–D), intergenic (E–J), or intragenic (K–O) regions. Overlap with TSSs identified in the TSS-seq data set or with statistically significant K4me3 or POLR2A peaks is indicated below each panel. y-axis value ranges, where not indicated, are 1–12 (ORC1); 1–30 (POLR2A and K4me3). RefSeq genes and RNA-seq tags are as of March 2011. Dashed lines in the RNA-seq track indicate picture clipping. (Scale bar) 5 kb.