Scatter plots showing the results from genotyping a panel of variant nucleotides in the factor V and the HLA-H genes. The SNPs from the FV gene had been selected from those described by Cargill et al. (1999). The polymorphism WIAF-10964 lies in exon 10 as the FV_Leidenmutation (Bertina et al. 1994), while the other SNPs are located in exon 13 of the gene. The polymorphism IVS2 lies in intron 2 (Beutler et al. 1997), the HH_C282Y mutation in exon 4 (Feder et al. 1996) and 5569A/G in intron 4 (Jeffrey et al. 1999) of the HLA-H gene. The six FV and two HLA-H gene SNPs, along with FV_Leiden and HH_C282Y mutations, were analyzed in 53 known FV_Leiden mutation and in 84 known HH_C282Y mutation carriers or homozygotes, and in 94 individuals known to be of normal genotype at both the mutant sites. The signal intensity ratios are given on the y-axis and the signal intensities on thex-axis.