Characteristic base contexts at C>A and C>T mutations in chondrosarcoma. Sequence logos of consensus surrounding sequences enriched at C>A (A) and C>T (B) mutations in chondrosarcoma (top left), prostate cancer (bottom left), melanoma (top right), and smoking-associated, small-cell lung cancer (bottom right). The x-axis indicates base position with respect to the mutation site (center, mutation; left, 5′ from the mutation; right, 3′ from the mutation). The y-axis indicates the information content at each position in the sequence.