Figure 3.

Analysis of prediction results for mutated promoters. (A) Promoters were divided into two groups depending on whether they were wild type (empty dots) or contained mutations (full dots) and plotted according to 1928inf35, where 1928inf36 is the predicted value of promoter i and participant p = 1,2…21, and 1928inf37 is the measured value for promoter i = 1,2…53. (B) Mutant promoter expression values were grouped according to the nature of the mutation and ordered by mean 1928inf38 value for each group. The six groups consist of mutations of TATA boxes (Δtata), of binding sites for Fhl1 (Δfhl1) and Sfp1 (Δsfp1), mutations to nucleosome disfavoring sequences (ΔNucDisf), random mutations (Random), and finally, sequences mutated intentionally with additional random mutations (Addition). The 1928inf39 value for each promoter is indicated by full dots; the mean value of 1928inf40 for each of the six grouped mutations is indicated by a thick bar. (C) For each mutated promoter i, 1928inf41 is plotted as a function of the percentage of expression value change induced in the wild-type promoter by the mutation. The vertical scale is logarithmic.

1928fig3