Sequence coverage. Coverage for 19 of the DNAs listed in Table 1 that were hybridized and sequenced on the same flow cell is shown for 500 bp of exon 11. Coverage bins of 5 bp were normalized to achieve the same amount of total coverage for each sample by multiplying by the appropriate factor (range = 0.70 to 2.7). DNA sample NA13707, which contains a heterozygous 40-bp deletion in this region (heavy black line); all others (thin gray lines). Numbering for the region is as found in the BIC database. The lowered coverage over a larger region than 40 bp and not centered on the deletion is caused by the presence of primers located entirely within or overlapping the deletion that generate no reads from those primers for the deletion allele.
