Fully combined RH network. (A) Co-retention between marker at 130,440,601 bp (blue arrow) on chromosome 2 and markers on chromosome 6 (left). Co-retention between marker at 57,433,004 bp (red arrow) on chromosome 6 and markers on chromosome 2 (right). (B) Gene–gene interactions at FDR <10⁻⁸. (C) Number of edges per gene (degree) for fully combined network at FDR <5%. Horizontal lines show hotspots (red, FDR <40%; green, FDR <1%) assuming a Poisson distribution (Brem and Kruglyak 2005; Park et al. 2008).