The 10-bp periodic digestion can be detected at individual genomic loci. (A) The combined read counts at individual bases shows the preference for a 10-bp spacing between reads in DNase-seq data, but not in FAIRE-seq data or in permuted DNase-seq data. The 91-bp nucleosome pattern used to identify DARNS (see Supplemental Fig. S3A) is superimposed on DNase-seq data. (B) Fourier analysis on 1000-bp windows from chromosome 1 reveals a prominent 10-bp period within DNase-seq data. (C) The same Fourier analysis on permuted data does not reveal a meaningful period.