Figure 2.
Neighbor joining tree of therian and platypus beta-defensins (DEFB1–6), in red, with chicken beta-defensins (Chick AvBD1–13) and platypus and reptile venom peptides. Chicken and therian sequences are shaded based on whether they belong to synteny groups A (yellow), B (blue), C (green), or D (pink). These synteny groups were determined by Patil et al. (2004) and Belov et al. (2007) based on genomic localization and phylogeny. Platypus DEFB1–5, which we have mapped to chromosome X2, belong to synteny group A, while platypus DEFB6, mapped to chromosome X1, belongs to synteny group D. Similar topologies were recreated using Baysian phylogenetics approaches.
