Figure 2.

Putative genes identified in the CES critical region (CESCR) and region of conserved synteny in mouse. Sequenced BACs and PACs (with GenBank accession nos.) are shown above (human) or below (mouse) the size scales. CpG islands in the human sequence, with their size in base pairs, are shown directly below the human size scale. Below this are the identified genes, with genes transcribed centromere to telomere above the chromosome, and genes transcribed telomere to centromere below the chromosome. The hatched section of chromosome 22 represents the region rich in duplications from other regions of the genome. The mouse genes are shown above the mouse size scale and oriented as described above. The banded section represents the portion of mouse chromosome 6 orthologous to human chromosome 12p13.

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