Hybridization of the 9p telomere clones, RG305J7 and RG41L13, labeled with digoxigenin and detected with anti-digoxigenin rhodamine (red), to normal metaphase chromosome preparations. (A) Clone RG305J7 shows a strong hybridization signal at the 9p telomere; additional signals are present on both sides of the pericentromeric region of chromosome 9 and at 2q13, the site of an ancestral telomere fusion. The chromosome 9 homologs are designated with arrows; the 2q13 signals are marked with arrowheads. (B) Hybridization with clone RG41L13 shows strong hybridization to the 9p telomere, indicated by arrows, with no cross-hybridization to any other chromosomes.