A comparative genomics display derived from the UCSC Genome Browser (Meyer et al. 2013). The top panel depicts the genomic region surrounding the 5′ end of the gene LBH (limb bud and heart development homolog) in the human genome. The top track indicates mammalian conservation as determined by phastCons (Pollard et al. 2010). Putative promoter and enhancer elements are indicated. The second track shows the intron/exon structure of the 5′ end of LBH. The 5′ untranslated region (UTR) and start site are indicated. The bottom panel shows a close up on the protein-coding portion of the first exon of LBH. Here, the top track shows the human DNA sequence, and the second track shows the degree of mammalian conservation as determined by PhyloP (Pollard et al. 2010). The bottom series of tracks shows the homologous protein sequence in selected vertebrate genomes. (N) Gaps in sequence; (=) unalignable sequence.
