Figure 1.

Overview of experimental framework to identify fusion transcripts in breast cancer genomes. (FGR) Transcripts in which exons from two distinct RefSeq genes are fused together in the same direction. (3′T-ER) Fusion transcripts in which the 3′-terminus portion of a given 5′ partner gene is truncated and fused to a non-RefSeq but annotated segment that has evidence for being part of a transcript. (3′T-NR) Any genomic segment that is in the anti-sense strand of any known gene/transcript or in an unannotated region that has no evidence for a transcript in current databases (see Supplemental Glossary).

676fig1