Global increase in Pol II density in spt4Δ does not result in increased transcript abundance in S. cerevisiae or S. pombe. (A,B) Box plots comparing the fold change in gene-body PRO-seq density resulting from the deletion of Spt4 with the corresponding change in poly-A selected RNA-seq in S. cerevisiae (A) and S. pombe (B). P-values represent the results of Student's t-test.