Promoter accessibility within the sox17E populations is consistent with presence of endodermal cell populations and lateral line neurons. (A) Heatmap of −log₁₀(adjusted P-value) from fishEnrichr Anatomy GeneRIF Predicted Z-score analyses of promoters showing greater accessibility in the comparisons indicated (FDR ≤ 0.05) as annotated by ChIPseeker. The key provides a continuous scale of −log₁₀(adjusted P-value), with minimum and maximum significance indicated, along with the 50th percentile significant value. Selected terms are shown; complete fishEnrichr outputs are in Supplemental Tables 9 and 10. (B) Dorsal widefield images of sox17:GFP embryo at 48 hpf. Nine focal layers have each been artificially colored based on depth from dorsal to ventral as indicated. (C) 3D rendering of confocal images 48 hpf sox17:GFP laterally orientated embryo with head to the left and tail to the right. Scale bar, 100 µm. (OC1) Organ of Corti 1; (plg) posterior lateral line ganglion; (primD) dorsal primordium; (primII) second primordium; (iv) intersegmental vessel; (L) liver; (P) pancreas; (dC) cells within duct of Cuvier; (pe) pharyngeal endoderm.