Table 2.

Transcripts Defining MMU10 Conserved Linkages with HSA19, 21, and 22

Mouse locus name Human locus name and aliases Genbank accession number Gene name Human location
Slc1a6[iv] SLC1A6, EAAT4 D83262 [ii] Solute carrier family 1, member 619p13.1
Aasl1[iv] AASSL1, 209L8 AI156588 [iii] Human homolog of acetolactate synthetase like gene19p13.1
D10Jhu34e[iv] No known human orthologs AI613583 [iii] Mouse EST 851439(19 or 21)[v]
Pdxk[iv] PDXK AI529482 [ii] Pyridoxal kinase21q22.3
Cstb CSTB, STFB Cystatin B21q22.3
Nnp1 NNP-1, D21S2056E Novel nuclear protein 121q22.3
D10Jhu12e Homology to human genomic sequence from 21q22.3 regionMouse EST 51509421q22.3
Tmem1 TMEM1 Transmembrane protein 121q22.3
Pwp2h[iv] PWP2H H50886 [ii] Yeast periodic tryptophan protein 2 homolog21q22.3
D10Jhu81e[iv] D21S2048E, GT335, HES1, hES1, KNP-Ia, KNP-Ib AA510875 [ii] Homolog of ES121q22.3
Aire1 AIRE, APECED, APS1, PGA I Autoimmune polyendocrinopathy syndrome, type I21q22.3
D10Jhu13e C21ORF2 mRNA mapping to APECED disease region (HSA 21q22.3)21q22.3
Pfkl PFKL, PFK Phosphofructokinase, liver type21q22.3
Trrp7[iv] TRPC7 NM003307[iii] Transient receptor potential-related channel 721q22.3
Krtap12-1 KRTAP12-1 High-cysteine keratin associated protein21q22.3
Ube2g2[iv] UBE2G2, UBC7 AA759396 [ii] Ubiquitin-conjugating enzyme E2G 221q22.3
Smt3h1 SMT3H1, SMT3A, SMT3 Supressor of mif two, 3 homolog 121q22.3
Itgb2 ITGB2, CD18 Integrin, beta-221q22.3
Adarb1 ADARB1, RED1 Adenosine deaminase, RNA-specific, B121q22.3
Col18a1 COL18A1 Collagen, type XVIII, alpha-121q22.3
Slc19a1 SLC19A1, FOLT, RFC1, IFC1 Solute carrier family 19, member 121q22.3
Col6a1 COL6A1 Collagen, type VI, alpha-121q22.3
Col6a2 COL6A2 Collagen, type VI, alpha-221q22.3
Lss LSS, OSC Lanosterol synthase21q22.3
D10Jhu64e[iv] No known human orthologs AA727480 [iii] Mouse EST 1210378(21q22.3)[v]
S100b S100B S100 calcium-binding protein, beta21q22.3
Prmt2 PRMT2, HRMT1L1 hnRNP methyltransferase-1-like 121q22.3
Mmp11 MMP11, STMY3 matrix metalloproteinase 1122q11.2
Mif MIF Macrophage migration inhibitory factor22q11.2
Gstt1 GSTT1 Glutathione S-transferase, theta 122q11.2
Ddt DDT D-dopachrome tautomerase22q11.2
Ppp3in[iv] PPP3IN,KIAA0330 AB002328 [iii] Protein phosphatase 3 inhibitor22q11–12
D10Jhu71e[iv] No known human orthologs AI615712 [iii] Mouse EST 974977(22q12)[v]
Ggt2[iv] GGT2 U30509 [ii] Gamma-glutamyl transpeptidase22q12

[i] Human map positions are from OMIM, GDB, and this analysis. Genes/ESTs are listed in the order that they appear on MMU10, telomeric to centromeric.

[ii] Accession number of sequence that was used to map the gene.

[iii] accession number of the EST/gene that was discovered from PAC end-sequence homology searches.

[iv] transcripts mapped for the first time in mouse.

[v] predicted location in human.