Table 1.

Tissue Divisions Used for STACK

dbEST 101598 Homo sapiens tissue partitioning
Arbitrary tissue partitions Substituent tissues types Total ESTs
Adiposebrown, white2,376
Brainfrontal lobe, cerebrum, cerebellum, cortex177,719
Cochleafetal cochlea4,304
Connectivebone, skin, synovial membrane40,753
Digestivestomach, colon, gall bladder51,032
Diseaseduplicates of ESTs annotated as tumors114,496
Eyeretina, cornea, ocular28,514
Genomicspecified chromosomes101,986
Glandsbreat, endocrine112,346
Heartfetal heart, aorta69,830
Hemato-lymphaticblood, kidney, liver–spleen255,565
Lungtrachea, larynx, lung70,259
Muscleleg, pectoral16,237
Olfactoryolfactory epithelium2,600
Othermonocytes, mononuclear cells25,925
Reproductiveovary, testis, uterus239,161

[i] Sequences were partitioned over an arbitrarily defined tissue hierarchy designed to group physically related tissues and remain within constraints of computational resources. Genomic tissue is a set of ESTs labeled only as having a genomic region of hybridization without a tissue source. The set of duplicate copies of all disease-related sequences is loosely referred to as a tissue for this work.