Table 1.

Upper Limit of 95% Confidence Interval for False-Positive Rate

Fold[i] False-positive rate (%)
β-propeller2.1
PLP-dependent transferases2.5
α/β-hydrolase2.8
SAM-methyltransferases3.0
Zn-β-lactamases3.3
Periplasmic-binding II3.4
Ferredoxin-like3.7
ATP-pyrophosphatases4.3
TIM-barrel5.3
P-loop NTPases5.6
RNase H-like5.8
NR-ligand binding6.1
Rossmann-like6.2
Protein kinases6.3
Flavodoxin-like7.6
Rossmann-fold9.6
ATP-grasp17.1
Class II aaRS and biotin synthetases23.9

[i] Abbreviated SCOP 1.35-fold names.