Genotype Distribution for Each Phenotype and Statistics for the Three Gene Intervals of Distal Chromosome 6
| Interval | Locus | Normal (1 + 2) | Insulitis (3 + 4) | Severe phenotype (5 + 6) | χ2 | Pvalue | |||||||
| N/N : N/P : P/P | N/N : N/P : P/P | N/N : N/P : P/P | |||||||||||
| Sex combined | |||||||||||||
| I | D6Mit21–11 | 75 : 26 : 11 | 11 : 9 : 1 | 63 : 28 : 17 | 1.55 | N.S. | |||||||
| II | D6Mit11–25 | 113 : 24 : 11 | 16 : 11 : 0 | 77 : 36 : 18 | 11.39 | 0.0005 | |||||||
| III | D6Mit25–26 | 128 : 25 : 18 | 20 : 8 : 2 | 99 : 40 : 15 | 2.82 | N.S. | |||||||
[i] Modification of the polychotomous linkage analysis allowed the NOD/NOD genotypes to be assessed against the pooled NOD/PWK + PWK/PWK genotypes for each histology class. This is a 1 degree of freedom test. Congenic interval analysis for distal chromosome 6.
[ii] (NS) Not significant.