Table 2.

Clusters of Plant R Genes Characterized by Molecular Analysis

R-gene locus Structural subclass[ii] Species Members of gene family[iii] Size of locus References
Cf2/Cf5 LRR–TMtomato 2+N.R. Jones et al. (1993); Dixon et al. (1996);  Hammond-Kosack and Jones (1997)
Cf4/Cf9 LRR–TMtomato 536 kb Jones et al. (1993); Parniske et al. (1997);  Thomas et al. (1997)
Dm3 NBS–LRRlettuce24+4 ± Mb Farrara et al. (1987); Meyers et al. (1998a)
Dm13 NBS–LRRlettuce13+N.R. Meyers (1998)
I2 NBS–LRRtomato 4+N.R. Ori et al. (1997)
M TIH–NBS–LRRflax15± <1 Mb Anderson et al. (1997); Ellis et al. (1997)
N TIH–NBS–LRRtobacco 4+N.R. Whitham et al. (1994)
Pto kinasetomato 5, plus Prf 65 ± kbD. Lavelle and R. Michelmore, (unpubl.)
RPP5 TIH–NBS–LRR Arabidopsis  750 ± kb Parker et al. (1996); Dangl and Holub (1997)
Xa21 LRR–kinaserice 8+230 ± kb Ronald et al. (1992); Song et al. (1995)

[i] (N.R.) not reported.

[ii] (TIH) Toll–interleukin homology region; (NBS) nucleotide binding site; (LRR) leucine-rich repeats; (TM) transmembrane domain.

[iii] Members of the gene family at each locus were determined in a single genotype by mapping of RFLPs resulting from the hybridization of the cloned resistance gene from that locus or by genomic sequencing of the region containing the cluster. This number includes pseudogenes.