Mouse–human comparative map. A map of the mouse genome and corresponding human homology regions. A map of the mouse genome is illustrated, with human homology regions indicated to theright of each map. The length of the chromosomes are delineated by crosshatch bars, which are spaced at 10-cM intervals along the mouse map. Human homology segments are labeled with the cytogenetic bands to which they map, as shown in Fig. 1. Conserved markers are placed to the left of the mouse map to provide anchor points for each homologous segment. Symbols and markings are identical to those described in the legend of Fig. 1. The positions of cloned mouse mutations, at left, and human diseases, atright of each map, are indicated by underlining and/or asterisks, are shown both here and in Fig. 1 for completeness and to aid in cross-referencing the two maps. Positions of additional mouse mutations, many of which are not cloned or solidly anchored to the human map, are also listed. On-line resources that aided the construction of Fig. 1 and this figure included MGD: The Mouse Genome Database (http://www.informatics.jax.org/mgd.html), Davis Human/Mouse Homology Map (http://www.ncbi.nlm.nih.gov/Homology/), and OMIM—Online Mendelian Inheritance in Man (http://www.ncbi.nlm.nih.gov/Omim/). Information regarding phenotypes, cloned genes, and other mutations that are not represented here can be obtained directly from these sources.