geneCover marker selection across three samples of the DLPFC data set. We apply generalized iterative geneCover with {k_t}_1:T = {100, 100, 100}, m = 3. (A) Annotated histological layers of three DLPFC tissue samples. (B) Normalized expression matrix of the selected geneCover markers across different layers in each sample. (C) Spatial expression (in log counts) patterns of the selected markers in sample #151507. (D) Same as C for sample #151669. (E) Same as C for sample #151673.