Table 3.

Run time performance for various assemblers presented in this paper

CPU hoursEstimated wall hours (64 vCPU)Peak RAM (GB)
Verkko8288.57129.561
Hifiasm366.95.7150
HapDup2425.024.0624
Shasta (UUL)582.49.11283
Read alignment307.24.8140
GFAse (Hi-C)75.02.384
GFAse (Pore-C)145.74.684
GFAse (trio)0.580.5830

[i] Separate times shown for GFAse Hi-C and Pore-C as a result of its dependence on the number of contacts. For HapDup, CPU hours and wall hours show the sum of multiple steps in the HapDup pipeline, including an initial Shasta assembly, which used 96 cores. GFAse trio runs single-threaded.