unCTC enables integrative analysis of CTCs and WBCs. A multistudy CTC/WBC data set was created to test the efficacy of unCTC alongside three best practice scRNA-seq analysis pipelines, namely, Vanilla Seurat, fastMNN, and Harmony. (A–C) Vanilla Seurat–based visualization, clustering, and cluster purity of CTCs and WBCs. (D–F) Similar figures for fastMNN. (G–I) Similar figures for Harmony. (J–L) Equivalent figures for unCTC.