[i] Calls overlapping with gaps in the reference genome are excluded from consideration. Two calls are concordant if they have >50% reciprocal overlap. The experimental FDR estimate for the CEPH child was done for calls generated with 50-bp binning. Numbers in parentheses are obtained from data self-consistency check, i.e., indirect estimation. Indirect estimation of sensitivity was calculated using Equation 5 in the Supplemental material. Sensitivity is measured with respect to RD-accessible CNVs (see definition in the Supplemental material).