Lcn2 is engaged with genomic loci in cis and in trans across the mouse genome before and after induction by Dex. Genomic map of Lcn2 contacts before (A) and 1 h after induction by Dex (B). Probes with P-values above the threshold (p score = −log₁₀ p > 4: 0.3% FDR) are labeled in a yellow-to-red color scale according to the intensity of the probe signal (log₂ 4C/genomic DNA). (Gray) Probes with P-values below the threshold.