Table 3.

Comparison of the TLR system across distant species

1112tbl3

aIn vertebrates, LRR-only genes like CD14 and C-type lectins like Dectin-1 (also known as CLEC7A) can be partners of TLRs in recognition, such as TLR4/CD14 complex for LPS and TLR2/TLR6/Dectin-1 complex for zymosan.